Endocrine Abstracts

Introduction: Differentiation between mild Cushing’s syndrome (CS) and Pseudo-Cushing syndrome (PCS) can be extremely difficult. A Pseudo-Cushing state can be defined as a part or all of the clinical features that resemble a true CS with some evidence of hypercotisolism but the resolution of the underlying primitive state results in the disappearance of this Cushing state-like. The aim of this work was to describe the diagnostic difficulties of 24 cases of PCS.<p clas...

Introduction: The management of diabetes goes through the education but also the management of acute and chronic complications. Among the complications, erectile dysfunction are too often forgotten as they actually affect the quality of life. The repercussions of this complication incite the clinician to look for it among the other complications of diabetes. The aim of our study is to evaluate the prevalence of erectile dysfunction in a diabetic population and to evaluate its ...

Introduction: Premature ovarian failure (POF) is defined as amenorrhea lasting more than four months before the age of 40 with a high level of gonadotropins in at least two separate samples. The aim of this work was to describe the etiological profile of a series of Tunisian women followed for POF.Patients and methods: It is a descriptive study of 42 cases of POF collected in the endocrinology department of Sousse between 2000 and 2017.<p class="abst...

Introduction: The therapeutic management of premature ovarian failure (POF) consists of a hormone replacement therapy that must be regular to avoid cardiovascular and bone complications as well as psychological management. The objective of this work was to study complications at 15 years of evolution of 42 tunisian women followed for POF.Patients and methods: It’s a retrospective study of 42 patients followed in the endocrinology department of Souss...

Introduction: Endocrine hypertension is the most common cause of secondary hypertension affecting nearly 3% of the population. Adrenal etiologies play a significant role in these cases. An adrenal incidentaloma is an asymptomatic adrenal tumor, at least one cm in diameter, discovered incidentally during a medical imaging examination. It requires an investigation into its secretory or malignant nature leading to the development of arterial hypertension.Ma...

Introduction: Endogenous Cushing’s disease is a serious and rare endocrine disorder. Medical therapy is mostly used as second-line treatment after failed surgery or recurrence and comprises several pituitary-directed drugs, glucocorticoid receptor blocker and adrenal steroidogenesis inhibitors such as osilodrostat. We here describe a case of a Tunisian patient with uncured cushing’s disease who developed iatrogenic adrenal insufficiency in the setting of Osilodrostat...

Introduction: Pseudopheochromocytoma is a poorly comprehended entity believed to arise from an overstimulated sympathetic nervous system. Individuals with pseudopheochromocytoma seem to demonstrate heightened cardiovascular reactivity to catecholamines, along with an increased release of epinephrine from the adrenal glands in response to stimulation from the sympathetic nervous system. This clinical report presents an observation of pseudopheochromocytoma in a patient diagnose...

Introduction: The adrenal incidentaloma is an asymptomatic tumor measuring at least one cm, discovered incidentally during a medical imaging examination. The adrenal incidentaloma continues to grow with technological advances and improved radiological examinations. Any adrenal incidentaloma involves the search for a secretion or malignant character. The objective of our study is to study the clinical, biological and etiological aspects of adrenal incidentalomas.<p class="a...

Introduction: Primary hyperparathyroidism JawTumor Syndrome is a rare genetic disorder characterized by the synchronous or metachronous occurrence of primary hyperparathyroidism and an ossifying fibroma of the maxilla and/or mandible, associated with an increased risk of parathyroid carcinoma.Observation: We report the case of a 30-year-old young woman who consulted for a limp in walking,6 months after having been operated for a juvenile ossifying fibrom...

Introduction: Gestational diabetes mellitus (GDM) arises from elevated glycemia during pregnancy, posing risks to both mother and fetus. Managing GDM involves close monitoring and dietary control, with antenatal insulin therapy (AIT). The aim of this study was to evaluate the efficiency of diverse maternal characteristics and biological indicators identified during GDM diagnosis in anticipating the inadequacy of dietary measures and the requirement for AIT to achieve glucose t...